The Radiation Oncology Research Laboratory (RORL) is the multi-disciplinary research arm of the Department of Radiation Oncology at the University of Maryland, Baltimore. The scientific faculty are primarily research orientated with some teaching responsibilities. They have joint appointments in the Greenebaum Cancer Center, as well as the Graduate Program in Molecular Medicine and Toxicology. The laboratory suites are located on the 6th and 7th floors of the Bressler Research Building and there are facilities for cellular and molecular biology, biochemistry, brightfield and fluorescence microscopy plus two radiation sources.
Radiation is a unique modality. On one hand it can cause cancer, and there is considerable public concern about possible health risks from low level radiation exposures around potentially contaminated nuclear weapons sites and the potential for nuclear terrorism. On the other hand, radiation has widespread public health applications including diagnostic radiology, cancer detection (mammography), food sterilization and nuclear power. In the Department of Radiation Oncology our physicians use radiation to treat cancer patients. At RORL radiation is used as a research tool for inducing programmed cell death (apoptosis), cell cycle checkpoints, and to damage the genetic material for studies of DNA repair.
RORLs research goals are to better understand the biological effects of radiation exposure with the ultimate objective of providing a rational scientific basis to improve radiation therapy for cancer patients. The research laboratories have strong ties to both the clinical and physics programs within the Department which considerably strengthens the translational component of our research emphasis.
There are 5 faculty members at RORL. Please use the Faculty links to the right to tour the labs.